Proteins,+Transcription,+and+Translation

The proteins in our body have a variety of types. They could be enzymes that help speed up the processes during chemical reactions. Some proteins are antibodies, protecting our bodies from infections. Other proteins also enable the body's muscles to contract, while some are hormonal proteins that help some of the body's movements. Also, there are structural proteins that provides support of your body parts. (Bailey, Regina)
 * __Purpose of Protein:__**

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=**__ Purpose of Protein In the Disorder:  __**= The Werner protein's (WRN) primary function is involved with DNA repair processes. WRN protein is a link between defective DNA repair and the processes involved in aging and cancer. (Oxford Journals) The protein in the disorder, the Werner protein, may divide slower or stop dividing earlier than normal, which causes growth problems. Also, the protein might damage the DNA, impairing the cell’s normal activities, causing health problems related to the disorder. (ASCO)

__** Transcription and Translation:  **__ Transcription is the first step in the process of Protein Synthesis (making of proteins). During transcription, the RNA polymerase (an enzyme) unwinds and separates the DNA strands. Then, the RNA polymerase adds and connects the RNA nucleotides to the DNA strand to make the mRNA. Then,the introns are removed from the strand, while the exons are spliced together to leave the nucleus. The mRNA strand leaves the nucleus to go to the ribosome for the translation part of the process. In translation, the mRNA strand is in the ribosome containing codons for making proteins. The tRNA goes to the ribosome, containing the anti-codons (complementary bases for the codons in the mRNA) and the amino acids that code for proteins. mRNA and the tRNA connect its nucleotides and the tRNA leaves the ribosome. Another tRNA molecule goes to the ribosome and does the same process. The amino acids form peptide bonds. The process keeps going until they reach a "stop" signal, and all the amino acids needed to make a certain protein are there.

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